Description

(3,5-Dichloropyridin-2-Yl)Methanamine Dihydrochloride is a high-purity, dihydrochloride salt derivative of a substituted pyridine, serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogenated pyridine scaffold introduces key structural and electronic properties. Its primary value lies in enabling the construction of complex molecules for pharmaceutical discovery and crop protection applications, requiring a reliable supply of high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the dichloropyridine moiety.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization (e.g., amide coupling, reductive amination) in medicinal and process chemistry.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized nitrogen-containing ligands for metal catalysis and coordination chemistry.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and functional polymers.

Basic Information

Product Name	(3,5-Dichloropyridin-2-Yl)Methanamine Dihydrochloride
CAS No.	1168139-51-2
Molecular Formula	C6H7Cl4N2
Molecular Weight	260.95 g/mol
Synonyms	2-(Aminomethyl)-3,5-dichloropyridine dihydrochloride; 1-(3,5-Dichloropyridin-2-yl)methanamine dihydrochloride; (3,5-Dichloro-2-pyridinyl)methanamine dihydrochloride; 3,5-Dichloro-2-pyridinemethanamine dihydrochloride; (3,5-Dichloro-pyridin-2-yl)-methylamine dihydrochloride; 2-(Aminomethyl)-3,5-dichloropyridine hydrochloride (1:2)
EINECS	Contact for details

Quality Control

Every batch of (3,5-Dichloropyridin-2-Yl)Methanamine Dihydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.