Description

Methyl 3-Chloro-2-Cyano-Pyridine-4-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring chloro, cyano, and ester functional groups on a pyridine core, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its pyridine-based bioactive scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and enzyme inhibition.

Basic Information

Product Name	Methyl 3-Chloro-2-Cyano-Pyridine-4-Carboxylate
CAS No.	1168102-35-9
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	Methyl 3-chloro-2-cyanopyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 3-chloro-2-cyano-, methyl ester; 3-Chloro-2-cyanoisonicotinic acid methyl ester; Methyl 3-chloro-2-cyanoisonicotinate; 3-Chloro-2-cyanopyridine-4-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2-Cyano-Pyridine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.