Description

3-Bromo-2-(4-(trifluoromethoxy)phenoxy)pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because it integrates a brominated pyridine core with a trifluoromethoxy-substituted phenoxy group, offering unique reactivity and physicochemical properties for creating complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand design, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the stability imparted by the trifluoromethoxy group.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis or for the synthesis of advanced organic electronic materials.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein function.

Basic Information

Product Name	3-Bromo-2-(4-(trifluoromethoxy)phenoxy)pyridine
CAS No.	1167991-25-4
Molecular Formula	C12H7BrF3NO2
Molecular Weight	334.09 g/mol
Synonyms	2-(4-(Trifluoromethoxy)phenoxy)-3-bromopyridine; 3-Bromo-2-(4-trifluoromethoxyphenoxy)pyridine; Pyridine, 3-bromo-2-[4-(trifluoromethoxy)phenoxy]-; 3-Bromo-2-(p-trifluoromethoxyphenoxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-(4-(trifluoromethoxy)phenoxy)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.