Description

3,6-Dihydro-2H-Pyridine-1-n-Boc-4-Boronic Acid Neopentylglycol Ester is a high-value, protected boronic ester derivative used as a key synthetic intermediate. This compound matters for its role in facilitating complex cross-coupling reactions, particularly in the synthesis of novel pharmaceutical candidates and advanced organic materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures. The CAS number for this compound is 1167991-21-0.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the discovery and development of new crop protection agents and herbicides.
• Material Science: Serves as a precursor for creating novel organic electronic materials and functional polymers.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
• Process Chemistry: Utilized in route scouting and optimization for scalable manufacturing of complex molecules.
• Academic Research: A valuable reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	3,6-Dihydro-2H-Pyridine-1-n-Boc-4-Boronic Acid Neopentylglycol Ester
CAS No.	1167991-21-0
Molecular Formula	C16H28BNO4
Molecular Weight	309.21 g/mol
Synonyms	1-Boc-3,6-dihydro-2H-pyridine-4-boronic acid neopentyl glycol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylate; 1-N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid neopentyl glycol ester; 1,2,3,6-Tetrahydropyridine-4-boronic acid pinacol ester, N-Boc protected; Boc-Protected 4-Borono-1,2,3,6-tetrahydropyridine Neopentyl Glycol Ester
EINECS	Contact for details

Quality Control

Our 3,6-Dihydro-2H-Pyridine-1-n-Boc-4-Boronic Acid Neopentylglycol Ester is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for demanding R&D and scale-up applications. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) with full analytical data are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated place, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.