Description

6-Iodo-5-Methyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated imidazopyridine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing.
• Biochemical Probe Synthesis: Employed in the creation of specialized molecular tools for investigating biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global pharmaceutical companies.

Basic Information

Product Name	6-Iodo-5-Methyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester
CAS No.	1167625-53-7
Molecular Formula	C11H11IN2O2
Molecular Weight	330.12 g/mol
Synonyms	Ethyl 6-Iodo-5-methylimidazo[1,2-a]pyridine-2-carboxylate; 6-Iodo-5-methylimidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 6-iodo-5-methyl-, ethyl ester; 1167625-53-7; Ethyl 6-iodo-5-methyl-imidazo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Iodo-5-Methyl-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.