Description

4-Chloro Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is a high-value, heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique fused pyrazolopyridine scaffold, functionalized with both a chloro substituent and a carboxylic acid group, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting various therapeutic areas, including oncology, central nervous system (CNS) disorders, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of molecular probes, enzyme inhibitors, and bioconjugation tools.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for exploring new chemical spaces in discovery programs.

Basic Information

Product Name	4-Chloro Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid
CAS No.	1167056-17-8
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	4-Chloro-1H-pyrazolo[1,5-a]pyridine-3-carboxylic acid; 4-Chloro-1H-pyrazolo[1,5-a]pyridine-3-carboxylic acid; 4-Chloropyrazolo[1,5-a]pyridine-3-carboxylic acid; 1167056-17-8; 4-Chloro-1H-pyrazolo[1,5-a]pyridine-3-carboxylic acid; Pyrazolo[1,5-a]pyridine-3-carboxylic acid, 4-chloro-
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research and development applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting critical parameters such as assay (HPLC), related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.