Description

(S)-tert-Butyl 2-(6-(Benzyloxy)-2-(tert-Butoxycarbonylamino)Hexyloxy)Acetate is a high-purity, chiral synthetic intermediate of significant importance in advanced pharmaceutical research and development. Its core value lies in its role as a key building block for the synthesis of complex, biologically active molecules, particularly peptides and peptidomimetics. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for drug discovery and process development. The CAS number for this compound is 1166394-93-9.

Application

This specialized intermediate is primarily utilized in sophisticated organic synthesis, enabling the creation of novel therapeutic agents.

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of peptide-based drugs and enzyme inhibitors.
• Peptidomimetic Synthesis: Used to construct non-peptide compounds that mimic the structure and function of natural peptides, enhancing metabolic stability and bioavailability.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) and benzyloxy (Bn) groups serve as orthogonal protecting groups for amines and alcohols, respectively, allowing for selective deprotection in multi-step syntheses.
• Medicinal Chemistry Research: Enables the exploration of structure-activity relationships (SAR) by providing a versatile scaffold for introducing structural diversity into lead compounds.
• Process Chemistry Development: Serves as a key intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Item	Detail
Product Name	(S)-tert-Butyl 2-(6-(Benzyloxy)-2-(tert-Butoxycarbonylamino)Hexyloxy)Acetate
CAS No.	1166394-93-9
Molecular Formula	C24H39NO6
Molecular Weight	437.57 g/mol
Synonyms	(S)-Boc-NH-(CH2)5-O-CH2-COO-tBu (Benzyl ether); (S)-2-((6-(Benzyloxy)hexyl)amino)-2-oxoethyl 2-methylpropanoate, Boc-protected; tert-Butyl (S)-2-(6-(benzyloxy)-2-((tert-butoxycarbonyl)amino)hexyloxy)acetate; (S)-N-Boc-6-(Benzyloxy)hexyl Glycine tert-Butyl Ester; Boc-Lys(Bzl)-OtBu derivative; Amino Acid Protecting Group Reagent; Chiral Boc-Protected Amino Alcohol Ester.
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 2-(6-(Benzyloxy)-2-(tert-Butoxycarbonylamino)Hexyloxy)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to prevent degradation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.