Description

2,3-Dichloro-n-(6-Methoxy-3-Pyridinyl)-3-[(4-Methylbenzyl)Sulfonyl]Acrylamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly within oncology and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, particularly in oncology research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• Active Pharmaceutical Ingredient (API) Development: Serves as a crucial building block in the final stages of API synthesis for clinical trial materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up for pharmaceutical clients.
• Biochemical Research: Potential use as a tool compound or inhibitor in probing specific biological pathways and enzyme functions.

Basic Information

Product Name	2,3-Dichloro-n-(6-Methoxy-3-Pyridinyl)-3-[(4-Methylbenzyl)Sulfonyl]Acrylamide
CAS No.	1164529-74-1
Molecular Formula	C17H16Cl2N2O4S
Molecular Weight	415.29 g/mol
Synonyms	2,3-Dichloro-N-(6-methoxypyridin-3-yl)-3-[(4-methylbenzyl)sulfonyl]prop-2-enamide; 2,3-Dichloro-3-((4-methylbenzyl)sulfonyl)-N-(6-methoxy-3-pyridinyl)acrylamide; Acrylamide, 2,3-dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylbenzyl)sulfonyl]-; (E/Z)-2,3-Dichloro-N-(6-methoxy-3-pyridinyl)-3-[(4-methylbenzyl)sulfonyl]acrylamide; CAS 1164529-74-1
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-n-(6-Methoxy-3-Pyridinyl)-3-[(4-Methylbenzyl)Sulfonyl]Acrylamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.