Description

1-(4-Bromopyridin-2-Yl)Cyclopropanecarbonitrile is a high-value brominated pyridine derivative and cyclopropane-containing nitrile building block. This compound is essential for advanced organic synthesis, offering a versatile scaffold for constructing complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and scale-up of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a critical building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and materials science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A potential monomer or additive for creating advanced polymers with specific electronic or structural properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom synthesis projects and library production.

Basic Information

Product Name	1-(4-Bromopyridin-2-Yl)Cyclopropanecarbonitrile
CAS No.	1163707-56-9
Molecular Formula	C9H7BrN2
Molecular Weight	223.07 g/mol
Synonyms	1-(4-Bromo-2-pyridinyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(4-bromo-2-pyridinyl)-; 1-(4-Bromopyridin-2-yl)cyclopropane-1-carbonitrile; 2-(1-Cyanocyclopropyl)-4-bromopyridine; 4-Bromo-2-(1-cyanocyclopropyl)pyridine
EINECS	Contact for details

Quality Control

Our 1-(4-Bromopyridin-2-Yl)Cyclopropanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee reliable performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.