Description

4-Bromo-2-(1-Methylcyclopropyl)Pyridine is a high-value brominated pyridine derivative featuring a unique 1-methylcyclopropyl substituent, which imparts significant steric and electronic properties. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic building block for constructing complex molecular architectures. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a molecular scaffold for probe discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-Bromo-2-(1-Methylcyclopropyl)Pyridine
CAS No.	1163707-47-8
Molecular Formula	C9H10BrN
Molecular Weight	212.09 g/mol
Synonyms	2-(1-Methylcyclopropyl)-4-bromopyridine; 4-Bromo-2-(1-methylcyclopropyl)pyridine; 4-Bromo-2-(methylcyclopropyl)pyridine; Pyridine, 4-bromo-2-(1-methylcyclopropyl)-; 1163707-47-8
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(1-Methylcyclopropyl)Pyridine adheres to stringent internal quality standards, ensuring batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for pharmaceutical applications and can provide material for regulatory filings upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.