Description

6-(Imidazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing imidazole and pyridine pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic structures.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Catalyst & Ligand Development: Utilized to synthesize novel N-heterocyclic carbene (NHC) precursors and complex ligands for transition metal catalysis.
• Academic & Contract Research: A vital reagent for methodological development in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	6-(Imidazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester
CAS No.	1163706-77-1
Molecular Formula	C14H18BN3O2
Molecular Weight	271.13 g/mol
Synonyms	6-(1H-Imidazol-1-yl)pyridine-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(imidazol-1-yl)pyridine; 6-(Imidazol-1-yl)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Imidazol-1-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 6-(1-Imidazolyl)-2-pyridineboronic acid pinacol ester; Boronic acid, B-[6-(1H-imidazol-1-yl)-2-pyridinyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 6-(Imidazol-1-Yl)Pyridine-2-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. We provide comprehensive analytical data, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry characterization. Certificates of Analysis (COA) detailing purity and impurity profiles are available upon request for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) when possible to maintain stability and purity. Keep container tightly sealed in a desiccated environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.