Description

4-Isopropoxy-3-Methoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a critical intermediate in modern synthetic organic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, making it an essential reagent for reliable Suzuki-Miyaura cross-coupling reactions. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing complex biaryl and heterobiaryl scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aryl-aryl linkages.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific biaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular architecture is crucial.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: A staple reagent in laboratories for methodological development and the exploration of new synthetic pathways in peer-reviewed research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for use in bespoke synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-Isopropoxy-3-Methoxyphenylboronic Acid, Pinacol Ester
CAS No.	1163700-41-1
Molecular Formula	C16H25BO4
Molecular Weight	292.18 g/mol
Synonyms	4-Isopropoxy-3-methoxyphenylboronic acid pinacol ester; (4-Isopropoxy-3-methoxyphenyl)boronic acid pinacol ester; 2-(4-Isopropoxy-3-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; B-(4-Isopropoxy-3-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane; 4-(Isopropoxy)-3-methoxybenzeneboronic acid pinacol ester; Pinacol (4-isopropoxy-3-methoxyphenyl)boronate
EINECS	Contact for details

Quality Control

Every batch of 4-Isopropoxy-3-Methoxyphenylboronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure it meets the high standards required for sensitive cross-coupling applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency, purity, and reliability. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/NMR), and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.