Description

3-Chloro-n-Phenyl-5-(Trifluoromethyl)-2-Pyridinamine is a high-purity, specialized pyridine derivative with a distinct trifluoromethyl and chloro substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex molecules. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the biological activity of the pyridine and trifluoromethyl groups.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Scaffold: Provides a versatile core structure for medicinal chemistry and combinatorial chemistry libraries, enabling rapid exploration of structure-activity relationships (SAR).
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs) due to its nitrogen-donor sites.

Basic Information

Product Name	3-Chloro-n-Phenyl-5-(Trifluoromethyl)-2-Pyridinamine
CAS No.	1163681-50-2
Molecular Formula	C12H8ClF3N2
Molecular Weight	272.65 g/mol
Synonyms	3-Chloro-N-phenyl-5-(trifluoromethyl)pyridin-2-amine; 2-Pyridinamine, 3-chloro-N-phenyl-5-(trifluoromethyl)-; 3-Chloro-5-(trifluoromethyl)-N-phenylpyridin-2-amine; 3-Chloro-N-phenyl-5-(trifluoromethyl)-2-aminopyridine; 3-Chloro-5-trifluoromethyl-2-anilinopyridine; 1163681-50-2; 3-Chloro-5-(trifluoromethyl)-N-phenyl-2-pyridinamine
EINECS	Contact for details

Quality Control

Our 3-Chloro-n-Phenyl-5-(Trifluoromethyl)-2-Pyridinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. The container should be kept tightly sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.