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2-Iodo-4-Methyl-3-Nitropyridine CAS NO 1163297-86-6


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CAS No.:1163297-86-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Iodo-4-Methyl-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique halogenated and nitrated pyridine structure, which provides versatile reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the synthesis of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating libraries of bioactive molecules.
  • Agrochemical Synthesis: Used in the preparation of novel pesticides, herbicides, and fungicides due to its reactive halogen and nitro functional groups.
  • Material Science Research: Serves as a precursor for the synthesis of specialized ligands, catalysts, and functional organic materials.
  • Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
  • Nucleophilic Substitution: The iodine atom can be readily displaced by various nucleophiles, enabling diverse functional group transformations.
  • Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name 2-Iodo-4-Methyl-3-Nitropyridine
CAS No. 1163297-86-6
Molecular Formula C6H5IN2O2
Molecular Weight 264.02 g/mol
Synonyms 3-Nitro-4-methyl-2-iodopyridine; 4-Methyl-3-nitro-2-iodopyridine; 2-Iodo-4-methyl-3-nitropyridine; Pyridine, 2-iodo-4-methyl-3-nitro-; Iodopyridine derivative; 1163297-86-6 (CAS); 2-I-4-M-3-NP (abbrev.)
EINECS Contact for details

Quality Control

Our 2-Iodo-4-Methyl-3-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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