Description

4-Methyl-n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Benzenesulfonamide is a high-value, synthetically versatile boronic ester derivative, serving as a critical building block in modern organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used to construct novel herbicide and fungicide candidates through targeted coupling reactions.
• Material Science: Building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology: Employed in the development of molecular probes and bioconjugates for target identification and validation.
• Catalyst Ligand Synthesis: Intermediate for the preparation of sophisticated ligand systems used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring specific, functionalized pyridine-boronate cores.

Basic Information

Product Name	4-Methyl-n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Benzenesulfonamide
CAS No.	1162681-06-2
Molecular Formula	C18H23BN2O4S
Molecular Weight	374.26 g/mol
Synonyms	4-Methyl-N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide; 5-[(4-Methylphenyl)sulfonyl]amino-3-pyridineboronic acid pinacol ester; 3-[[(4-Methylphenyl)sulfonyl]amino]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Benzenesulfonamide, 4-methyl-N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]-; 1162681-06-2
EINECS	Contact for details

Quality Control

Our 4-Methyl-n-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Benzenesulfonamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.