Description

5-Fluoro-2-Methyl-3-Nitro-Pyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring fluorine and nitro substituents on a methylated pyridine core, enables precise molecular modifications critical for developing novel active ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new drug candidates, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated drug molecules targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a versatile scaffold for constructing complex ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials due to its electron-withdrawing nitro group and fluorine substitution.
• Chemical Biology & Proteomics: Utilized as a building block for creating molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for client projects.

Basic Information

Product Name	5-Fluoro-2-Methyl-3-Nitro-Pyridine
CAS No.	1162674-71-6
Molecular Formula	C6H5FN2O2
Molecular Weight	156.11 g/mol
Synonyms	3-Nitro-5-fluoro-2-picoline; 2-Methyl-5-fluoro-3-nitropyridine; 5-Fluoro-2-methyl-3-nitropyridine; 5-Fluoro-3-nitro-2-picoline; 2-Picoline, 5-fluoro-3-nitro-; 1162674-71-6; 5-Fluoro-2-methyl-3-nitro-pyridine
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-Methyl-3-Nitro-Pyridine undergoes rigorous analytical testing to ensure it meets the high-purity standards required for research and scale-up applications. Our quality assurance protocols are designed to guarantee batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.