Description

2,4-Difluoro-5-Methylbenzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its role in introducing specific fluorine and ester functionalities into complex molecular architectures, enabling precise control over physical and chemical properties. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates requiring fluorinated aromatic motifs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the difluoro-methylbenzoate structure can contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, potentially altering surface properties, chemical resistance, and thermal stability.
• Chemical Research & Development: A versatile reagent for academic and industrial research in medicinal chemistry, materials science, and methodology development involving cross-coupling and functional group transformations.

Basic Information

Item	Details
Product Name	2,4-Difluoro-5-Methylbenzoic Acid Methyl Ester
CAS No.	1162674-66-9
Molecular Formula	C10H8F2O2
Molecular Weight	198.17 g/mol
Synonyms	Methyl 2,4-Difluoro-5-methylbenzoate; 5-Methyl-2,4-difluorobenzoic Acid Methyl Ester; Benzoic acid, 2,4-difluoro-5-methyl-, methyl ester; 2,4-Difluoro-5-methyl-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Methylbenzoic Acid Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.