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6-(Trifluoromethyl)Pyridin-2-Yl-2-Boronic Acid CAS NO 1162257-61-5


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CAS No.:1162257-61-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-(Trifluoromethyl)Pyridin-2-Yl-2-Boronic Acid is a high-value boronic acid derivative and a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the versatile 6-(trifluoromethyl)pyridin-2-yl moiety into target molecules.

Application

  • Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with enhanced metabolic stability and bioavailability.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate the trifluoromethylpyridine group for improved efficacy.
  • Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
  • Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and semiconductors, where its structural motif can tune electronic properties.
  • Chemical Biology & Probe Design: Utilized in the synthesis of molecular probes and bio-conjugates for studying biological systems and diagnostic applications.
  • Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name 6-(Trifluoromethyl)Pyridin-2-Yl-2-Boronic Acid
CAS No. 1162257-61-5
Molecular Formula C6H5BF3NO2
Molecular Weight 190.92 g/mol
Synonyms 2-(6-(Trifluoromethyl)pyridin-2-yl)boronic acid; (6-(Trifluoromethyl)pyridin-2-yl)boronic acid; 6-(Trifluoromethyl)-2-pyridineboronic acid; 2-Borono-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)pyridine-2-boronic acid; 2-Pyridineboronic acid, 6-(trifluoromethyl)-; B-[6-(Trifluoromethyl)-2-pyridinyl]boronic acid
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Quality Control

Our 6-(Trifluoromethyl)Pyridin-2-Yl-2-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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