Description

Ethyl5,5-Difluoro-4-Oxopentanoate is a high-purity fluorinated ketoester building block, essential for advanced organic synthesis. Its unique difluorinated structure offers significant value in modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated analogs of bioactive molecules, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and pesticides with enhanced efficacy and environmental profile.
• Fluorine Chemistry Research: Serves as a versatile precursor for introducing the CF2 group into complex molecular architectures via various transformations.
• Material Science: Potential building block for specialty polymers and advanced materials requiring specific fluorine-based properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific fluorinated compounds under cGMP or research-grade conditions.

Basic Information

Product Name	Ethyl5,5-Difluoro-4-Oxopentanoate
CAS No.	1161004-57-4
Molecular Formula	C7H10F2O3
Molecular Weight	180.15 g/mol
Synonyms	Ethyl 5,5-difluoro-4-oxopentanoate; 4-Oxopentanoic acid, 5,5-difluoro-, ethyl ester; 5,5-Difluoro-4-oxopentanoic acid ethyl ester; Ethyl 5,5-difluoro-4-oxovalerate; 1161004-57-4; Difluorinated ketoester; Ethyl difluorolevulinate
EINECS	Contact for details

Quality Control

Our Ethyl5,5-Difluoro-4-Oxopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.