Description

6-Bromo-2,4-Dichloropyrrolo[2,1-F][1,2,4]Triazine is a high-purity, multi-halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its unique halogenated triazine-pyrrole scaffold.
• Material Science: Acts as a building block for creating novel organic electronic materials, such as semiconductors or light-emitting compounds.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Heterocyclic Chemistry: A versatile starting material for further functionalization and annulation reactions to access more complex polyheterocyclic systems.

Basic Information

Product Name	6-Bromo-2,4-Dichloropyrrolo[2,1-F][1,2,4]Triazine
CAS No.	1160995-23-2
Molecular Formula	C6HBrCl2N4
Molecular Weight	272.91 g/mol
Synonyms	6-Bromo-2,4-dichloropyrrolo[2,1-f][1,2,4]triazine; 2,4-Dichloro-6-bromopyrrolo[2,1-f][1,2,4]triazine; Pyrrolo[2,1-f][1,2,4]triazine, 6-bromo-2,4-dichloro-; 1160995-23-2; 6-Bromo-2,4-dichloro-pyrrolo[2,1-f][1,2,4]triazine; SCHEMBL21806227; BRN 14988977
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,4-Dichloropyrrolo[2,1-F][1,2,4]Triazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.