Description

tert-Butyl [3-(5'-(Trifluoromethy)Lpyridin-2'-Yl)-[1,2,4]Methyl]- -Carbamate is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylpyridine and carbamate functional groups. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate fluorinated motifs for enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates targeting various therapeutic areas, leveraging the trifluoromethyl group for improved pharmacokinetic properties.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with enhanced potency and selectivity.
• Agrochemical Synthesis: Serves as a building block for developing advanced crop protection agents, where the pyridine and fluorine atoms contribute to biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales under GMP conditions where applicable.

Basic Information

Product Name	tert-Butyl [3-(5'-(Trifluoromethy)Lpyridin-2'-Yl)-[1,2,4]Methyl]- -Carbamate
CAS No.	1160994-72-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl 3-(5-(trifluoromethyl)pyridin-2-yl)-1,2,4-oxadiazol-5-ylmethylcarbamate; 1,1-Dimethylethyl N-[[3-[5-(trifluoromethyl)-2-pyridinyl]-1,2,4-oxadiazol-5-yl]methyl]carbamate; BOC-Protected (5-(Trifluoromethyl)pyridin-2-yl)-1,2,4-oxadiazole Methylamine; CAS 1160994-72-8; tert-Butyl N-({3-[5-(trifluoromethyl)pyridin-2-yl]-1,2,4-oxadiazol-5-yl}methyl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl [3-(5'-(Trifluoromethy)Lpyridin-2'-Yl)-[1,2,4]Methyl]- -Carbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.