Description

5-Bromo-3-Hydroxypicolinonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring bromine, hydroxyl, and nitrile functional groups on a pyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where it serves as a key scaffold for structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated heterocyclic structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science: Acts as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Bromo-3-Hydroxypicolinonitrile
CAS No.	1160936-51-5
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	5-Bromo-3-hydroxypyridine-2-carbonitrile; 3-Hydroxy-5-bromopicolinonitrile; 2-Cyano-5-bromo-3-hydroxypyridine; 5-Bromo-3-pyridinol-2-carbonitrile; 5-Bromo-2-cyano-3-pyridinol
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Hydroxypicolinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.