Description

5-Bromo-4-Chloronicotinonitrile is a high-value halogenated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its precise molecular architecture makes it indispensable for constructing complex heterocyclic scaffolds, enabling the development of novel compounds with targeted properties. This building block is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Material Science: Serves as a building block for creating specialized ligands, organic semiconductors, and functional polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized pyridine motifs into more complex molecular structures.
• Academic & Contract Research: Utilized in medicinal chemistry programs and process research for exploring new synthetic pathways and compound libraries.

Basic Information

Product Name	5-Bromo-4-Chloronicotinonitrile
CAS No.	1160923-98-7
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	4-Chloro-5-bromonicotinonitrile; 5-Bromo-4-chloro-3-cyanopyridine; 3-Cyano-5-bromo-4-chloropyridine; Nicotinonitrile, 5-bromo-4-chloro-; 1160923-98-7; 5-Br-4-Cl-nicotinonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloronicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.