Description

5-Bromo-4-Hydroxynicotinonitrile is a versatile and high-purity brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an invaluable intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for creating functionalized ligands in coordination chemistry and advanced polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the bromo and hydroxynitrile functionalities into target molecules.
• Academic & R&D: A valuable reagent for medicinal chemistry programs and exploratory research in heterocyclic chemistry.

Basic Information

Product Name	5-Bromo-4-Hydroxynicotinonitrile
CAS No.	1160923-97-6
Molecular Formula	C6H3BrN2O
Molecular Weight	199.01 g/mol
Synonyms	5-Bromo-4-hydroxypyridine-3-carbonitrile; 4-Hydroxy-5-bromonicotinonitrile; 3-Cyano-5-bromo-4-hydroxypyridine; 5-Bromo-4-hydroxy-3-pyridinecarbonitrile; 1160923-97-6; 5-Bromo-4-hydroxynicotinonitrile
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Hydroxynicotinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.