Description

tert-Butyl 4-((6-Bromopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile building block for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates, especially in oncology and neurology research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a critical building block in the pilot-scale and commercial-scale production of complex Active Pharmaceutical Ingredients (APIs).
• Bioconjugation & Probe Synthesis: Utilized in the development of chemical probes and bioconjugates for biochemical and diagnostic applications.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring bromopyridine and piperazine motifs.

Basic Information

Product Name	tert-Butyl 4-((6-Bromopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate
CAS No.	1160923-86-3
Molecular Formula	C16H24BrN3O2
Molecular Weight	370.29 g/mol
Synonyms	1-Boc-4-((6-bromopyridin-3-yl)methyl)piperazine; tert-Butyl 4-[(6-bromo-3-pyridinyl)methyl]-1-piperazinecarboxylate; 4-((6-Bromopyridin-3-yl)methyl)piperazine-1-carboxylic acid tert-butyl ester; 1-Piperazinecarboxylic acid, 4-[(6-bromo-3-pyridinyl)methyl]-, 1,1-dimethylethyl ester; BOC-4-((6-Bromo-3-pyridyl)methyl)piperazine; 1160923-86-3
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-((6-Bromopyridin-3-Yl)Methyl)Piperazine-1-Carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.