Description

4-Chloro-5-Iodo-6-Methylnicotinonitrile is a halogenated pyridine derivative, specifically a substituted nicotinonitrile, that serves as a versatile and high-value synthetic intermediate. Its molecular structure, featuring chlorine and iodine substituents, makes it a critical building block for constructing complex heterocyclic systems in medicinal chemistry and advanced materials science. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive pyridine core.
• Ligand Synthesis: Serves as a starting material for creating complex ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Advanced Material Development: Building block for organic electronic materials, such as those used in OLEDs or semiconductors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for custom chemical synthesis projects.

Basic Information

Product Name	4-Chloro-5-Iodo-6-Methylnicotinonitrile
CAS No.	1160848-89-4
Molecular Formula	C7H4ClIN2
Molecular Weight	278.48 g/mol
Synonyms	4-Chloro-5-iodo-6-methylpyridine-3-carbonitrile; 3-Cyano-4-chloro-5-iodo-6-methylpyridine; 6-Methyl-4-chloro-5-iodonicotinonitrile; 4-Chloro-5-iodo-6-methyl-3-pyridinecarbonitrile; 5-Iodo-4-chloro-6-methylnicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-5-Iodo-6-Methylnicotinonitrile is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.