Description

3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine is a high-value, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds to attach the tetrahydropyrazolopyridine core to various aryl and heteroaryl halides.
• Agrochemical Research: Used in the development of new active ingredients for crop protection with potential insecticidal or fungicidal properties.
• Material Science Precursor: Serves as a monomer or functional unit in the design of organic electronic materials and advanced polymers.
• Chemical Biology Probe Synthesis: Utilized to create labeled compounds or molecular probes for studying biological pathways and target engagement.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries to identify new lead structures in drug discovery.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine
CAS No.	1160614-73-2
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	4,5,6,7-Tetrahydropyrazolo[1,5-a]pyridine-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine; 3-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine; 3-Pinacolatoboryl-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine; 3-Boronic acid, 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine adheres to stringent quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation, to ensure compliance with research and development grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a dry, cool environment. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.