Description

Methyl 3-Bromo-5-Chloro-4-Iodobenzoate is a highly functionalized benzoate ester derivative, serving as a critical multi-halogenated building block in advanced organic synthesis. Its precise halogen substitution pattern makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those targeting specific receptors where halogen atoms are crucial for binding affinity and metabolic stability.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the halogenated aromatic core can contribute to biological activity and environmental persistence profiles.
• Material Science: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution, enabling rapid diversification of chemical libraries.
• Academic & R&D: Essential reagent for methodological studies in organic chemistry, exploring new catalytic systems and reaction pathways involving polyhalogenated arenes.

Basic Information

Product Name	Methyl 3-Bromo-5-Chloro-4-Iodobenzoate
CAS No.	1160574-80-0
Molecular Formula	C8H5BrClIO2
Molecular Weight	374.39 g/mol
Synonyms	Methyl 3-bromo-5-chloro-4-iodobenzoate; Benzoic acid, 3-bromo-5-chloro-4-iodo-, methyl ester; 3-Bromo-5-chloro-4-iodobenzoic acid methyl ester; Methyl 3-bromo-5-chloro-4-iodobenzoate; Methyl ester of 3-bromo-5-chloro-4-iodobenzoic acid
EINECS	Contact for details

Quality Control

Our Methyl 3-Bromo-5-Chloro-4-Iodobenzoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC-MS, and NMR for comprehensive characterization and purity verification. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.