Description

Ethyl 6-Bromo-2-(Trifluoromethyl)-2H-Chromene-3-Carboxylate is a high-value fluorinated chromene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the strategic combination of a bromo-substituent and a trifluoromethyl group, enabling precise functionalization and the introduction of desirable physicochemical properties into target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex heterocyclic scaffolds for new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic materials with tailored optical or electronic properties.
• Chemical Biology Probe Development: Utilized to create fluorescent tags or molecular probes for studying biological processes and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and fluorination chemistry.

Basic Information

Product Name	Ethyl 6-Bromo-2-(Trifluoromethyl)-2H-Chromene-3-Carboxylate
CAS No.	1160474-50-9
Molecular Formula	C13H10BrF3O3
Molecular Weight	351.12 g/mol
Synonyms	Ethyl 6-Bromo-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylate; 2H-1-Benzopyran-3-carboxylic acid, 6-bromo-2-(trifluoromethyl)-, ethyl ester; 6-Bromo-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid ethyl ester; Ethyl 6-bromo-2-trifluoromethylchromene-3-carboxylate; 1160474-50-9; 6-Bromo-2-(trifluoromethyl)-2H-1-benzopyran-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-2-(Trifluoromethyl)-2H-Chromene-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with precise specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound should be handled as a moisture-sensitive material. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.