Description

tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Pyrrolidine-3,3'-Quinoline]-1-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with potential activity in central nervous system and other therapeutic areas. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and lead optimization.
• API Development: Serves as a critical building block in the multi-step synthesis of novel Active Pharmaceutical Ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying spirocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Pyrrolidine-3,3'-Quinoline]-1-Carboxylate
CAS No.	1160247-71-1
Molecular Formula	C17H20N2O3
Molecular Weight	300.36 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-2',4'-dihydro-1'H-spiro[pyrrolidine-3,3'-quinoline]-2'-one; tert-Butyl 1,2',4',9'-tetrahydrospiro[pyrrolidine-3,3'-quinoline]-1'-carboxylate 2'-oxide; 1-Boc-2',4'-dihydrospiro[pyrrolidine-3,3'-quinoline]-2'-one; Spiro[pyrrolidine-3,3'-quinoline]-1-carboxylic acid, 2',4'-dihydro-2'-oxo-, 1,1-dimethylethyl ester; 1160247-71-1; BOC-Spiroquinoline; tert-Butyl spiroquinoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2'-Oxo-2',4'-Dihydro-1'H-Spiro[Pyrrolidine-3,3'-Quinoline]-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled and stored away from strong acids and organic solvents to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.