Description

tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate is a high-value, nitrogen-containing spirocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel chemical space and the development of new therapeutic agents. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing advanced scaffolds in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, protease inhibitors, and other small-molecule therapeutics.
• Medicinal Chemistry Scaffold: Used to create diverse compound libraries for high-throughput screening (HTS) and structure-activity relationship (SAR) studies due to its three-dimensional, spirocyclic structure.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents, including fungicides and herbicides, where its unique heterocyclic core can impart novel biological activity.
• Chemical Biology Probe Development: Utilized as a core structure for designing molecular probes to study biological pathways and protein function.
• Process Chemistry & Scale-up: Serves as a starting material or intermediate in the optimization and commercial-scale production of complex target molecules.

Basic Information

Product Name	tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate
CAS No.	1160247-36-8
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	6-Boc-2,6-diazaspiro[3.5]nonane; 2,6-Diazaspiro[3.5]nonane-6-carboxylic acid, 1,1-dimethylethyl ester; tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate; 2,6-Diazaspiro[3.5]nonane, 6-Boc-protected; Boc-2,6-diazaspiro[3.5]nonane; 6-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.5]nonane; 1,1-Dimethylethyl 2,6-diazaspiro[3.5]nonane-6-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.