Description

7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-(Aminomethyl)-, 1,1-Dimethylethyl Ester is a high-value, protected amino acid derivative featuring a unique spirocyclic structure, making it a critical advanced pharmaceutical intermediate (API) for modern drug discovery. Its primary value lies in serving as a sophisticated building block for the synthesis of complex molecules, particularly in medicinal chemistry. This compound is essential for research and development teams in the pharmaceutical and biotechnology sectors focused on creating novel therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Peptidomimetic Chemistry: Used to construct constrained peptide analogs and peptidomimetics, enhancing metabolic stability and biological activity in drug candidates.
• Medicinal Chemistry & Drug Discovery: Employed as a versatile scaffold for library synthesis in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material for custom synthesis projects and the production of specialized fine chemicals under cGMP conditions.

Basic Information

Product Name	7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-(Aminomethyl)-, 1,1-Dimethylethyl Ester
CAS No.	1160247-15-3
Molecular Formula	C14H26N2O2
Molecular Weight	254.37 g/mol
Synonyms	tert-Butyl 2-(aminomethyl)-7-azaspiro[3.5]nonane-7-carboxylate; 2-(Aminomethyl)-7-azaspiro[3.5]nonane-7-carboxylic acid tert-butyl ester; 7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-(aminomethyl)-, 1,1-dimethylethyl ester; Boc-7-azaspiro[3.5]nonane-2-methylamine; (2-(Aminomethyl)-7-azaspiro[3.5]nonan-7-yl)(tert-butoxy)methanone
EINECS	Contact for details

Quality Control

Our 7-Azaspiro[3.5]Nonane-7-Carboxylic Acid, 2-(Aminomethyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.