Description

6-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,6-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic amine class. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and oncological pathways. It is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical and biotechnology industries who require reliable, high-quality intermediates for complex multi-step syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with spirocyclic or constrained amine structures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical building block for scaling up the production of target APIs under Good Manufacturing Practice (GMP) conditions.
• Neurological Drug Synthesis: Employed in the development of compounds targeting central nervous system (CNS) disorders.
• Oncology Drug Development: Used as a scaffold in the creation of potential anticancer agents.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	6-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,6-Dicarboxylate
CAS No.	1160247-10-8
Molecular Formula	C20H29N3O4
Molecular Weight	375.47 g/mol
Synonyms	2,6,9-Triazaspiro[4.5]decane-2,6-dicarboxylic acid, 2-(1,1-dimethylethyl) 6-(phenylmethyl) ester; 2-tert-Butyl 6-benzyl 2,6,9-triazaspiro[4.5]decane-2,6-dicarboxylate; tert-Butyl benzyl 2,6,9-triazaspiro[4.5]decane-2,6-dicarboxylate; 6-Benzyl 2-tert-butyl 2,6,9-triazaspiro[4.5]decane-2,6-dicarboxylate; CAS 1160247-10-8; Spirocyclic Amine Ester Intermediate; Bn-Boc-2,6,9-Triazaspiro[4.5]decane Derivative
EINECS	Contact for details

Quality Control

Our 6-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,6-Dicarboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to ICH Q7 guidelines and can support development from research grade through to GMP standards for clinical and commercial supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.