Description

tert-Butyl 8-Oxo-2,6,9-Triazaspiro[4.5]Decane-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and heterocyclic scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its structural complexity which enables the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, especially for central nervous system (CNS) and oncology targets.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or core component in the design of heterobifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Synthesis: Used in the construction of complex heterocyclic cores found in potential kinase inhibitor libraries.
• Chemical Biology Research: Employed as a molecular scaffold for probing protein-ligand interactions and developing chemical probes.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of complex, proprietary compounds for clients in the life sciences sector.

Basic Information

Product Name	tert-Butyl 8-Oxo-2,6,9-Triazaspiro[4.5]Decane-2-Carboxylate
CAS No.	1160247-09-5
Molecular Formula	C12H21N3O3
Molecular Weight	255.32 g/mol
Synonyms	2,6,9-Triazaspiro[4.5]decane-2-carboxylic acid, 8-oxo-, 1,1-dimethylethyl ester; tert-Butyl 8-oxo-2,6,9-triazaspiro[4.5]decane-2-carboxylate; 8-Oxo-2,6,9-triazaspiro[4.5]decane-2-carboxylic acid tert-butyl ester; 2-(tert-Butoxycarbonyl)-2,6,9-triazaspiro[4.5]decan-8-one; 2-Boc-2,6,9-triazaspiro[4.5]decan-8-one; 2-N-Boc-2,6,9-triazaspiro[4.5]decan-8-one; Spirocyclic Boc-protected amine; 1160247-09-5
EINECS	Contact for details

Quality Control

Our tert-Butyl 8-Oxo-2,6,9-Triazaspiro[4.5]Decane-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with cGMP guidelines for advanced pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.