Description

9-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,9-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic amine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or ligands in targeted protein degradation platforms.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific compounds under cGMP conditions.

Basic Information

Product Name	9-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,9-Dicarboxylate
CAS No.	1160247-08-4
Molecular Formula	C21H31N3O4
Molecular Weight	389.49 g/mol
Synonyms	2,6,9-Triazaspiro[4.5]decane-2,9-dicarboxylic acid, 9-(phenylmethyl)-, 1,1-dimethylethyl ester; 2-(tert-Butoxycarbonyl)-9-(benzyloxycarbonyl)-2,6,9-triazaspiro[4.5]decane; Boc-Cbz-2,6,9-Triazaspiro[4.5]decane; 9-Benzyl 2-tert-butyl 2,6,9-triazaspiro[4.5]decane-2,9-dicarboxylate; tert-Butyl 9-(benzyloxycarbonyl)-2,6,9-triazaspiro[4.5]decane-2-carboxylate; N-Boc-N'-Cbz-2,6,9-Triazaspiro[4.5]decane; 2,6,9-Triazaspiro[4.5]decane-2,9-dicarboxylate, benzyl tert-butyl ester
EINECS	Contact for details

Quality Control

Our 9-Benzyl 2-tert-Butyl 2,6,9-Triazaspiro[4.5]Decane-2,9-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.