Description

tert-Butyl 3-Oxo-1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic lactam class of compounds. This molecule serves as a critical building block in modern medicinal chemistry, enabling the synthesis of complex, bioactive molecules with enhanced pharmacological profiles. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent protease inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities (NCEs).
• API Synthesis: Integral in constructing the complex spirocyclic core of active pharmaceutical ingredients (APIs) for clinical trials.
• CNS Drug Development: Employed in research programs targeting neurological conditions due to its ability to cross the blood-brain barrier.
• Oncology Research: Serves as a scaffold for developing novel kinase inhibitors and other anticancer agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Item	Details
Product Name	tert-Butyl 3-Oxo-1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate
CAS No.	1160247-07-3
Molecular Formula	C14H24N2O4
Molecular Weight	284.35 g/mol
Synonyms	9-Boc-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane; tert-Butyl 3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane-9-carboxylate; 1-Oxa-4,9-diazaspiro[5.5]undecane-3-one, 9-(1,1-dimethylethyl) ester; 9-(tert-Butoxycarbonyl)-3-oxo-1-oxa-4,9-diazaspiro[5.5]undecane; BOC-Protected Spirocyclic Lactam; 1160247-07-3; Spiro[5.5]lactam intermediate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Oxo-1-Oxa-4,9-Diazaspiro[5.5]Undecane-9-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for advanced research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere such as nitrogen after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.