Description

7-(tert-Butoxycarbonyl)-1-Oxa-2,7-Diazaspiro[4.4]Non-2-Ene-3-Carboxylic Acid CAS NO 1160247-02-8 is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of novel therapeutics, particularly for central nervous system (CNS) and metabolic disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting protease inhibition and receptor modulation.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Drug Discovery Programs: Integral to the development of potential treatments for neurological conditions, such as anxiety, depression, and neurodegenerative diseases.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study specific biological pathways and enzyme functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	7-(tert-Butoxycarbonyl)-1-Oxa-2,7-Diazaspiro[4.4]Non-2-Ene-3-Carboxylic Acid
CAS No.	1160247-02-8
Molecular Formula	C13H20N2O5
Molecular Weight	284.31 g/mol
Synonyms	1-Oxa-2,7-diazaspiro[4.4]non-2-ene-3-carboxylic acid, 7-[(1,1-dimethylethoxy)carbonyl]-; Boc-Protected 1-Oxa-2,7-Diazaspiro[4.4]Non-2-Ene-3-Carboxylic Acid; 7-Boc-1-Oxa-2,7-Diazaspiro[4.4]Non-2-Ene-3-Carboxylic Acid; tert-Butyl 3-carboxy-1-oxa-2,7-diazaspiro[4.4]non-2-ene-7-carboxylate; Spirocyclic Amino Acid Derivative; CAS 1160247-02-8
EINECS	Contact for details

Quality Control

Our production of 7-(tert-Butoxycarbonyl)-1-Oxa-2,7-Diazaspiro[4.4]Non-2-Ene-3-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to quality supports compliance with the standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.