Description

8-(1,1-Dimethylethyl) 1-Oxa-8-Azaspiro[4.5]Decane-3,8-Dicarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel therapeutic agents, especially for central nervous system (CNS) disorders.
• Organic Synthesis Building Block: Used to construct complex molecular architectures in medicinal chemistry and academic research due to its spirocyclic and heterocyclic framework.
• Ligand and Catalyst Development: Serves as a scaffold for developing novel ligands or organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents with specific biological activity.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or functional materials requiring specific heterocyclic components.

Basic Information

Product Name	8-(1,1-Dimethylethyl) 1-Oxa-8-Azaspiro[4.5]Decane-3,8-Dicarboxylate
CAS No.	1160246-97-8
Molecular Formula	C15H25NO5
Molecular Weight	299.36 g/mol
Synonyms	tert-Butyl 3-(methoxycarbonyl)-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1-Oxa-8-azaspiro[4.5]decane-3,8-dicarboxylic acid, 8-(1,1-dimethylethyl) ester; 8-tert-Butyl 3-methyl 1-oxa-8-azaspiro[4.5]decane-3,8-dicarboxylate; Spirocyclic Ester Intermediate; CAS 1160246-97-8
EINECS	Contact for details

Quality Control

Our 8-(1,1-Dimethylethyl) 1-Oxa-8-Azaspiro[4.5]Decane-3,8-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring material that meets ICH guidelines and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.