Description

2-Oxa-7-Azaspiro[4.5]Decane-3,7-Dicarboxylic Acid7-tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral therapeutic areas. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex spirocyclic and heterocyclic active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the creation of novel molecular scaffolds targeting specific biological pathways.
• CNS Drug Synthesis: Serves as a precursor in the development of therapeutics for neurological and psychiatric disorders.
• Antiviral Agent Research: Employed in the research and synthesis of potential antiviral compounds due to its structural complexity.
• Chemical Biology: Used as a probe or tool compound in studying enzyme mechanisms and protein-ligand interactions.
• Process Chemistry: Scalable intermediate for GMP (Good Manufacturing Practice) production of clinical trial materials and commercial APIs.

Basic Information

Product Name	2-Oxa-7-Azaspiro[4.5]Decane-3,7-Dicarboxylic Acid7-tert-Butyl Ester
CAS No.	1160246-92-3
Molecular Formula	C14H23NO5
Molecular Weight	285.34 g/mol
Synonyms	7-tert-Butyl 2-oxa-7-azaspiro[4.5]decane-3,7-dicarboxylate; 2-Oxa-7-azaspiro[4.5]decane-3,7-dicarboxylic acid, 7-(1,1-dimethylethyl) ester; 7-tert-Butyl 3,7-dicarboxy-2-oxa-7-azaspiro[4.5]decane; tert-Butyl 3,7-dioxo-2-oxa-7-azaspiro[4.5]decane-7-carboxylate; Spirocyclic Oxazolidinone Ester; Azaspiro[4.5]decane Derivative; CAS 1160246-92-3
EINECS	Contact for details

Quality Control

Our 2-Oxa-7-Azaspiro[4.5]Decane-3,7-Dicarboxylic Acid7-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.