Description

tert-Butyl 3-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) therapeutics and other specialized drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular libraries in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of potential active pharmaceutical ingredients (APIs) requiring a functionalized spirocyclic amine moiety.
• Chemical Biology Probes: Employed in the development of specialized probes for studying biological pathways and enzyme interactions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl 3-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate
CAS No.	1160246-91-2
Molecular Formula	C13H24N2O3
Molecular Weight	256.34 g/mol
Synonyms	8-Boc-3-amino-1-oxa-8-azaspiro[4.5]decane; 3-Amino-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; tert-Butyl 3-amino-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-amino-, 1,1-dimethylethyl ester; Boc-3-amino-1-oxa-8-azaspiro[4.5]decane; 1160246-91-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.