Description

1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic and heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing complex heterocyclic libraries for high-throughput screening.
• API Synthesis: Integral to the multi-step synthesis of potential therapeutic agents targeting neurological pathways.
• Process Chemistry Development: Serves as a standard in scaling up synthetic routes from laboratory to pilot plant scale.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and receptor interactions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.

Basic Information

Product Name	1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	1160246-89-8
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	tert-Butyl 3-oxo-1-oxa-7-azaspiro[4.5]decane-7-carboxylate; 7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[4.5]decan-3-one; 1-Oxa-7-azaspiro[4.5]decane-7-carboxylic acid, 3-oxo-, 1,1-dimethylethyl ester; Boc-1-oxa-7-azaspiro[4.5]decan-3-one; 3-Oxo-1-oxa-7-azaspiro[4.5]decane-7-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Oxa-7-Azaspiro[4.5]Decane-7-Carboxylic Acid, 3-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is manufactured and tested in facilities that implement cGMP (current Good Manufacturing Practice) principles where applicable. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.