Description

Benzyl 1,8-Diazaspiro[4.6]Undecane-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the diazaspiroalkane class of compounds. This molecule is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex spirocyclic architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, including potential treatments for central nervous system (CNS) disorders and other specialized medical applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug molecules, especially those with spirocyclic frameworks.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) targeting neurological and psychiatric conditions.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Can be utilized in the development of specialized probes for studying biological pathways and enzyme functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects on behalf of pharmaceutical clients.

Basic Information

Product Name	Benzyl 1,8-Diazaspiro[4.6]Undecane-8-Carboxylate
CAS No.	1160246-79-6
Molecular Formula	C17H22N2O2
Molecular Weight	286.37 g/mol
Synonyms	Benzyl 1,8-Diazaspiro[4.6]undecane-8-carboxylate; 8-(Benzyloxycarbonyl)-1,8-diazaspiro[4.6]undecane; 1,8-Diazaspiro[4.6]undecane-8-carboxylic acid benzyl ester; Cbz-Protected 1,8-Diazaspiro[4.6]undecane; Z-1,8-Diazaspiro[4.6]undecane
EINECS	Contact for details

Quality Control

Our Benzyl 1,8-Diazaspiro[4.6]Undecane-8-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.