Description

tert-Butyl 1,3-Dioxo-2,7-Diazaspiro[4.5]Decane-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and diazepine-dione scaffold. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and process scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel heterocyclic compounds in drug discovery programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of synthetic routes for potential APIs under Good Manufacturing Practice (GMP) guidelines.
• Proteolysis Targeting Chimera (PROTAC) Development: May be employed as a component in the linker or ligand design for targeted protein degradation therapeutics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis projects.

Basic Information

Product Name	tert-Butyl 1,3-Dioxo-2,7-Diazaspiro[4.5]Decane-7-Carboxylate
CAS No.	1160246-76-3
Molecular Formula	C13H20N2O4
Molecular Weight	268.31 g/mol
Synonyms	7-Boc-2,7-diazaspiro[4.5]decane-1,3-dione; tert-Butyl 1,3-dioxo-2,7-diazaspiro[4.5]decane-7-carboxylate; 2,7-Diazaspiro[4.5]decane-1,3-dione, 7-(1,1-dimethylethyl) ester; 7-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.5]decane-1,3-dione; Boc-DAD; Boc-2,7-diazaspiro[4.5]decane-1,3-dione
EINECS	Contact for details

Quality Control

Our tert-Butyl 1,3-Dioxo-2,7-Diazaspiro[4.5]Decane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.