Description

tert-Butyl 2-Oxo-1,7-diazaspiro[4.4]nonane-7-carboxylate is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting therapeutic areas such as central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The diazaspiro[4.4]nonane structure is relevant for designing inhibitors targeting specific enzymatic pathways.
• Chemical Biology Probes: Employed in the development of tool compounds for investigating biological mechanisms and target validation.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.
• Library Synthesis: Used to generate diverse compound libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	tert-Butyl 2-Oxo-1,7-diazaspiro[4.4]nonane-7-carboxylate
CAS No.	1160246-72-9
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	7-Boc-2-oxo-1,7-diazaspiro[4.4]nonane; tert-Butyl 2-oxo-1,7-diazaspiro[4.4]nonane-7-carboxylate; 1,7-Diazaspiro[4.4]nonane-7-carboxylic acid, 2-oxo-, 1,1-dimethylethyl ester; 2-Oxo-1,7-diazaspiro[4.4]nonane-7-carboxylic acid tert-butyl ester; Boc-Protected 2-oxo-1,7-diazaspiro[4.4]nonane; 7-(tert-Butoxycarbonyl)-2-oxo-1,7-diazaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Oxo-1,7-diazaspiro[4.4]nonane-7-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.