Description

tert-Butyl 1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate is a high-value, spirocyclic building block and advanced pharmaceutical intermediate. This compound matters for its crucial role in the synthesis of complex bioactive molecules, particularly in modern drug discovery programs targeting challenging disease pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, especially within medicinal chemistry for hit-to-lead and lead optimization stages.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile spirocyclic scaffold for constructing compound libraries in drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or component in the design of bifunctional degraders.
• Kinase Inhibitor Synthesis: Employed in the construction of complex heterocyclic cores found in kinase inhibitor candidates.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the cGMP or non-GMP production of clinical trial materials.

Basic Information

Item	Detail
Product Name	tert-Butyl 1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate
CAS No.	1160246-71-8
Molecular Formula	C12H20N2O3
Molecular Weight	240.30 g/mol
Synonyms	6-Boc-2,6-diazaspiro[3.5]nonan-1-one; tert-Butyl 1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate; 2,6-Diazaspiro[3.5]nonane-1-one, 6-(1,1-dimethylethyl) ester; 6-(tert-Butoxycarbonyl)-2,6-diazaspiro[3.5]nonan-1-one; Boc-2,6-diazaspiro[3.5]nonan-1-one; 1-Oxo-2,6-diazaspiro[3.5]nonane-6-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-oxo-2,6-diazaspiro[3.5]nonane-6-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Specifications are aligned with the needs of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the material at 2-8°C under an inert atmosphere to maintain optimal stability. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.