Description

3-Cyclopropyl-4-(Difluoromethyl)-7-Methylisoxazolo[5,4-B]Pyridin-6(7H)-One is a high-value, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its unique fused isoxazolopyridine scaffold, functionalized with cyclopropyl and difluoromethyl groups, makes it a versatile building block for constructing novel bioactive molecules. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Agrochemical Development: Serves as a precursor in the research and production of new pesticides and herbicides, leveraging its heterocyclic core.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Cyclopropyl-4-(Difluoromethyl)-7-Methylisoxazolo[5,4-B]Pyridin-6(7H)-One
CAS No.	1160246-39-8
Molecular Formula	C12H10F2N2O2
Molecular Weight	252.22 g/mol
Synonyms	3-Cyclopropyl-4-(difluoromethyl)-7-methyl-[1,2]oxazolo[5,4-b]pyridin-6-one; 7-Methyl-3-cyclopropyl-4-(difluoromethyl)isoxazolo[5,4-b]pyridin-6(7H)-one; 1160246-39-8; 3-Cyclopropyl-4-(difluoromethyl)-7-methylisoxazolo[5,4-b]pyridin-6-ol; Isoxazolo[5,4-b]pyridin-6(7H)-one, 3-cyclopropyl-4-(difluoromethyl)-7-methyl-
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropyl-4-(Difluoromethyl)-7-Methylisoxazolo[5,4-B]Pyridin-6(7H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specification parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.