Description

Ethyl (5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetate is a high-purity pyrazolopyridine derivative, a crucial advanced pharmaceutical intermediate (API) for modern drug discovery and development. This compound is valued for its role as a versatile synthetic building block, enabling the creation of novel therapeutic agents with targeted biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of innovative small-molecule drugs, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific disease pathways.
• Kinase Inhibitor Development: Used in research and production of potential kinase inhibitors for cancer therapy and other proliferative diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Reagent: Employed in biochemical assays and as a reference standard for analytical method development and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	Ethyl (5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetate
CAS No.	1160246-38-7
Molecular Formula	C11H13N3O2
Molecular Weight	219.24 g/mol
Synonyms	Ethyl 2-(5-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate; 1H-Pyrazolo[3,4-b]pyridine, 1-(acetyloxy)ethyl ester; Ethyl (5-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)ethanoate; 5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl-acetic acid ethyl ester; CAS 1160246-38-7; Pyrazolopyridine acetate ester; 1-(Ethoxycarbonylmethyl)-5-methyl-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our Ethyl (5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.