Description

3-(5-Methyl-2H-Pyrazolo[3,4-B]Pyridin-2-Yl)Propanenitrile is a high-purity, heterocyclic organic compound featuring a fused pyrazolopyridine core, serving as a critical advanced pharmaceutical intermediate. Its molecular architecture makes it a valuable synthon for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new molecular entities.
• Kinase Inhibitor Development: Serves as a core scaffold in the research and synthesis of kinase inhibitors due to the privileged pyrazolopyridine structure.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides.
• Fine Chemical Production: Used in custom synthesis and the manufacture of complex, high-value specialty chemicals.
• Biochemical Tool Compound: Potential use in developing probes for biological target identification and validation.

Basic Information

Product Name	3-(5-Methyl-2H-Pyrazolo[3,4-B]Pyridin-2-Yl)Propanenitrile
CAS No.	1160246-33-2
Molecular Formula	C10H10N4
Molecular Weight	186.22 g/mol
Synonyms	3-(5-Methyl-2H-pyrazolo[3,4-b]pyridin-2-yl)propanenitrile; 2H-Pyrazolo[3,4-b]pyridine, 3-(2-cyanoethyl)-5-methyl-; 3-(5-Methyl-2H-pyrazolo[3,4-b]pyridin-2-yl)propionitrile; 5-Methyl-2-(2-cyanoethyl)-2H-pyrazolo[3,4-b]pyridine; Propanenitrile, 3-(5-methyl-2H-pyrazolo[3,4-b]pyridin-2-yl)-
EINECS	Contact for details

Quality Control

Our 3-(5-Methyl-2H-Pyrazolo[3,4-B]Pyridin-2-Yl)Propanenitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.