Description

1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound is of significant commercial importance due to its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of proprietary drug candidates and investigational new drugs (INDs).
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic frameworks with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial research programs focusing on kinase inhibitors, anti-cancer agents, and other targeted therapies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for scale-up and cGMP production.
• Chemical Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1160246-29-6
Molecular Formula	C12H15N3O3
Molecular Weight	249.27 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 6,7-dihydro-1-(1-methylethyl)-3-methyl-6-oxo-; 1-Isopropyl-3-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6,7-Dihydro-1-isopropyl-3-methyl-6-oxo-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; CAS 1160246-29-6; Fused Pyrazolopyridine Carboxylic Acid Derivative
EINECS	Contact for details

Quality Control

Our production of 1-Isopropyl-3-Methyl-6-Oxo-6,7-Dihydro-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.