Description

(5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of targeted therapeutics for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel therapeutic targets.
• Organic Synthesis: Serves as a versatile precursor for constructing complex fused heterocyclic systems in academic and industrial R&D.
• Biochemical Tool Compound: Potential use in the development of probes and assay components for biological screening.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid
CAS No.	1160246-25-2
Molecular Formula	C9H9N3O2
Molecular Weight	191.19 g/mol
Synonyms	1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 5-methyl-; 2-(5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; (5-Methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 5-Methyl-1H-pyrazolo[3,4-b]pyridine-1-acetic acid; 1160246-25-2; 5-Methylpyrazolopyridine acetic acid derivative
EINECS	Contact for details

Quality Control

Our production of (5-Methyl-1H-Pyrazolo[3,4-B]Pyridin-1-Yl)Acetic Acid adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with cGMP and ISO guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is stable under these conditions but should be handled in accordance with good laboratory practices for strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.